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noun

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fatigue - Extreme tiredness, typically resulting from mental or physical exertion or illness

After working for 15 hours straight, a strong cup of coffee did nothing to help Jolene's fatigue.

adjective

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skittish - (of an animal, especially of a horse) excitable or easily scared

Bill's horse was especially skittish around people it didn't know, so they had to be careful when Bill's friend Fred wanted to stroke the horse's mane.

adjective

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desperation - A strong feeling of fear and loss of hope.

Their credit card debt was so large, that they felt a sense of desperation about being able to fix the situation.

adjective

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aggravating - Causing annoyance, irritation, and frustraton by repeated annoying behavior.

It’s so aggravating when people talk loudly during a movie.

noun

See verb

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gasp - A convulsive catching of breath

Abe let out a sharp gasp after he had remained underwater for ten seconds.

adjective

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achy - Experiencing a dull, persistent pain in the body, often due to illness or tiredness.

The construction worker's achy muscles were a sign that he needed a vacation.