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derail - To obstruct or divert from an expected or intended course.

The train was derailed by a fallen tree during the storm.

verb

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shackle - Something that prevents freedom of movement, literally or figuratively

Because John had so much debt, he felt he couldn't consider switching careers, and therefore felt shackled to a job that he hated.

verb

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intervene - To come between two people, groups, or events to prevent or change an outcome.

The teachers had to intervene when the students started arguing in the school yard.

verb

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kibosh - When an idea or plan is spoiled or stopped, often due to unforseen circumstances.

Keith was going to go to the museum, but his sudden illness put the kibosh on his plans.

verb

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subside - To become less intense, violent, or severe; to gradually decrease and go down to a lower level.

After the winds and rain of the hurricane finally subsided, people could see the damage that was left behind.

noun

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mortality - The state of being human and not living for ever

When we think about the inevitabilty of our own mortality, it makes us more committed to make good use of every minute.

verb

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pardon - To forgive someone for a crime or wrongdoing, and end imprisonment or bad feelings.

The president decided to pardon the prisoner after reviewing the case.

noun

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hiatus - A temporary gap, pause, break, or absence when something stops happening.

His vacation in Alaska with his wife was a wonderful and exciting hiatus between their very stressful jobs.

verb

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deter - To prevent (or aim to prevent) the occurrence of something through fear of consequences.

A barking dog can deter burglars from breaking into a home.

noun

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impediment - Something that obstructs or slows down progress; a hindrance or obstacle.

His lack of funding was a major impediment to starting his business.