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jarring - Causing a sudden, unpleasant, or shocking effect.

The loud and sudden fire alarm was jarring in the otherwise quiet neighborhood.

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uneasy - Feeling anxious, worried, or uncomfortable about something; feeling a sense of discomfort or restlessness.

She felt uneasy walking alone through the dark alley.

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sweltering - Uncomfortably hot

In India during the summer, the sweltering heat literally melted the roads.

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queasy - Feeling nervous, uneasy, or anxious.

After the stock he bougtht kept going down, he felt queasy and thought perhaps he had made a bad decision.

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colicky - Having severe abdominal pain, often caused by spasm, obstruction, or distention of any of the hollow viscera, such as the intestines

Pam's crying baby was colicky because of intestinal problems.

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squeamish - (of a person) easily made to feel sick, faint, or disgusted, especially by unpleasant images, such as the sight of blood

Nico was so squeamish about receiving a flu shot that he broke out into a sweat.