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impoverished - Very poor.

We can hardly imagine how impoverished the average person was during the Middle Ages.

noun

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shackles - A device, such as a chain or cuff, designed to physically limit or control a person or thing's movement.

Shackles were placed on the prisoner's feet so that he would not be able to run away and escape.

noun

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throes - Intense or violent pain and struggle, especially accompanying birth, death, or great change

Samantha experienced agonizing pain during the throes of childbirth.

verb

See noun

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torment - Cause to experience severe mental or physical suffering

William enjoyed tormenting his younger sister until she would run away and complain to their mother.

noun

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pang - A sudden sharp pain or painful emotion

The year was 1900, and Dmitri felt a pang of nostalgia and regret as he boarded the boat for America, knowing that he would probably never see his 'old world' again.

noun

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affliction - Something that causes pain or suffering.

When Pharoah didn't let the people go, Moses gave Egypt one affliction after another.

noun

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hardship - Severe suffering or difficulty caused by lack of necessities like food, money, or shelter.

Many families are facing economic hardship due to rising living costs.

adjective

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grueling - Extremely tiring and demanding

Troops go through grueling training before they can finally serve their country.

verb

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flinch - To make a quick, nervous movement of the face or body as an instinctive reaction to surprise, fear or pain

Debbie was very brave and didn’t flinch when the nurse put the needle in her arm to give her the flu shot.

verb

See noun

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plague - To cause constant worry, annoyance, or distress, often by repeatedly confronting someone with problems or challenges.

She was plagued by constant headaches, making it hard for her to focus on her work.

verb

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degenerate - To decline or deteriorate physically, mentally, or morally

After Bill started taking drugs, his life went downhill until his his relationships, health, and finances had totally degenerated.

adjective

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excruciating - Intensely painful

Becky had to see the dentist because her toothache was causing her excruciating pain.