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noun

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agony - Extreme physical or mental suffering

Max was in physical agony as he rode his bicycle up the long mountain trail, but spiritually and emotionally he was in heaven.

verb

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plague - To cause constant worry, annoyance, or distress, often by repeatedly confronting someone with problems or challenges.

She was plagued by constant headaches, making it hard for her to focus on her work.

adjective

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impoverished - Very poor.

We can hardly imagine how impoverished the average person was during the Middle Ages.

verb

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wince - To give a slight involuntary grimace or shrinking movement of the body out of or in anticipation of pain or distress

Tiger winced as he realized he had hit the ball too far beyond the hole.

noun

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plight - A difficult or unfortunate situation, often one that involves hardship or adversity.

The community came together to help improve the plight of the homeless during the harsh winter months.

adjective

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grueling - Extremely tiring and demanding

Troops go through grueling training before they can finally serve their country.

noun

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inflammation - A physical condition characterized by redness, heat, swelling, and pain, often as a response to injury or infection.

The redness of the big toe was caused by an infection, and the inflammation was visible and painful.

adjective

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strenuous - Requiring great effort, energy, or strength, needing vigorous or intense in activity or action.

Hiking up the mountain was a strenuous task, but the view was worth it.

adjective

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tragic - Something very sad often involving suffering.

The story of how Oedipus mistakenly killed his father and married his mother is a tragic story.

noun

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pang - A sudden sharp pain or painful emotion

The year was 1900, and Dmitri felt a pang of nostalgia and regret as he boarded the boat for America, knowing that he would probably never see his 'old world' again.

adjective

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excruciating - Intensely painful

Becky had to see the dentist because her toothache was causing her excruciating pain.

adjective

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agonizing - Something that causes great physical or mental pain.

After she took the final exam, it was agonizing to her that for a whole week she wouldn't find out the results.