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substantial - Of considerable importance, size, or worth; or strongly built or solid in structure.

They named the building after him because he made a substantial donation to the charity.

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phenomenal - Very remarkable; extraordinary

Mark Zuckerberg started Facebook in his Harvard dorm room, and turned it into one of the largest companies in the world, and everyone would agree that that Facebook has been a phenomenal success.

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ramifications - The possible results of an action

Being Aristotle's student, Alexander the Great was able to plan out a military strategy taking into account all its ramifications.

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supreme - (of authority or an office, or someone holding it) superior to all others

In Iran, the Ayatollah is the supreme ruler who controls the country's population.

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utmost - The greatest or highest degree or amount of something; as far as possible; to the maximum extent

During the emergency, the authoriies emphasized that it is of the utmost importance that people follow the safety guidelines.

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comprehensive - Complete; including all or nearly all elements or aspects of something.

The Master's program in finance was a comprehensive program that enables Bill to graduate and get a job right away as an accountant.

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urgent - Requiring immediate attention or action; something that needs to be dealt with quickly.

The doctor said his arm was broken, and that it was urgent that he get it treated right away.

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momentous - Important because of the effect it has on the future

Neil Armstrong's first step on the moon was a momentous event because it gave people the feeling that nothing was beyond their reach.

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caliber - The quality or standard of someone's ability or character.

The company is looking to hire engineers of top caliber.

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mission - A journey or action taken for a particular purpose, often of importance.

The rescue team was sent on a mission to save the trapped hiker.

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crucial - Of central and extreme importance

As they left for the plane, the parents knew it was crucial that all the members of the family had their passports.

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bigwig - A VIP (very important person) or influential decision-maker, often used informally.

Only the bigwigs got access to the exclusive boardroom on the top floor of the company's headquarters.